TheSemiconductor LayerFor Pharma

Building the frontier of pharmaceutical risk infrastructure. Human cardiac organoids and high-resolution genomics, surfacing drug-induced cardiac injury before it reaches a patient.

The Problem

Heart failure is a leading damaging effect and one of the most elusive to catch before the damage is done. Today's preclinical tools surface that risk years and hundreds of millions too late.

90%

of oncology drugs fail in trial

≤50%

of truly cardiotoxic drugs missed by today's standard tools

$300M

lost per failed drug

Our Solution

Our platform is the first of its kind to take this approach.

  • Human organoids

    Biomanufactured cardiac tissue, QC'd batch to batch

  • Drug exposure

    Your compound, run against living tissue

  • Risk genomics

    High-resolution readout paired with pharmacodynamic risk

The product

Actionable go/no-go reports.

Every angle of risk captured against your compound, synthesized into a definitive answer on where to move the candidate next.

Three inputs — biomanufactured human cardiac organoids, exposure of those organoids to the client’s compound, and high-resolution risk genomics — converge into a single predictive go/no-go briefing.
Who We Serve

  • AI-enabled drug discovery teams
  • Safety and toxicology R&D teams

We stand as the bridge between bench, clinic, and bedside — grounding high-conviction decisions with insight that otherwise blindsides you too late to act on.

Our Mission

Human-genome-backed resolution, so you see it before it becomes hindsight.

Cardiotoxicity remains one of the leading causes of late-stage drug failure, resulting in significant development delays, patient risk, and millions of dollars in lost R&D investment.

The field is moving fast, and it knows the urgency. What it lacks are tools that can keep pace. We give it that resolution — clearing the low-lying cardiac risk that holds innovation back, so therapies can move faster and with more confidence.

Our Team

Operator-built. Execution-focused.

We combine scientific architecture and commercial strategy to ensure you get the best product, every time.

LinkedIn
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Backers & Partners

Henry Ford Health logo

Early Backer

Henry Ford Health

Advaita Bioinformatics logo

Partner

Advaita Bioinformatics

Contact

Cardiac risk, answered before the clinic.

If you are evaluating a compound with cardiac exposure — or building the models that will — we should talk.